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The areas of science and mathematics have traditionally been inaccessible to students with Visual Impairment. Hence it needs adapted materials and instructional methods to understand and perform science experiments by visually impaired. This study aims to study the Effectiveness of Adapted Science Instruction on Leaning of Science Temperature Concept among students with Visual Impairment. The Investigator adapted the Science Temperature concept Activities as per the needs of Students with Visual Impairment. Visually Impaired sample from Grade VI to VIII were trained and effectivess of the Adapted Instruction was found.